Product Name: Propylene Glycol BIO
Chemical Name: 1,2-Propanediol
Synonyms: BioPG, 1,2-Dihydroxypropane, Methyl glycol
Recommended Uses: Pharmaceuticals, Food additives, Cosmetics, Industrial applications
Supplier Details: Manufacturer contact information with emergency numbers
CAS Number: 57-55-6
EC Number: 200-338-0
Classification: Not classified as hazardous under GHS
Physical Hazards: Does not support combustion under standard conditions
Health Hazards: Can cause mild eye irritation, rarely causes skin irritation, not considered sensitizing
Environmental Hazards: Low risk to aquatic environments under normal use
Label Elements: No hazard pictograms required
Signal Word: None
Precautionary Statements: Avoid direct eye contact, rinse thoroughly if exposed
Chemical Name: Propylene Glycol
Concentration: ≥99.5% by weight
Impurities: Trace water, organic acids (very low ppm range), compliance with food/pharma grade regulations
Molecular Formula: C3H8O2
Molecular Weight: 76.09 g/mol
Inhalation: Move to fresh air; seek medical attention for discomfort or symptoms
Skin Contact: Wash thoroughly with soap and water; no adverse effects expected under routine use
Eye Contact: Rinse immediately with plenty of water for several minutes; remove contact lenses; consult physician if irritation persists
Ingestion: Rinse mouth, give water, do not induce vomiting, seek medical advice if large amount swallowed or symptoms appear
Most Important Symptoms and Effects: Minor irritation to skin or eyes may occur; ingestion may rarely cause nausea or upset stomach in sensitive individuals
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Do not use water jet directly on product
Special Hazards: At high temperatures, may burn and produce oxides of carbon
Firefighter Protection: Wear full protective gear and self-contained breathing apparatus in enclosed spaces
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, aldehydes (in case of incomplete combustion)
Personal Precautions: Ensure adequate ventilation, avoid eye contact, use protective gear
Environmental Precautions: Prevent large spills from entering drains or waterways
Containment Methods: Stop leak if safe, use sand or inert absorbent materials to soak up spill
Cleanup Procedures: Collect and dispose of in accordance with local regulations, wash area with water after material pickup
Reporting Requirements: Comply with local rules for environmentally significant spills
Handling: Handle in a well-ventilated area, avoid direct contact with eyes or prolonged skin exposure
Storage Conditions: Store in original container in a cool, dry place away from heat and direct sunlight
Incompatibilities: Do not store near strong oxidizers or acids, avoid storing with reactive metals
Hygiene Practices: Wash hands after handling, do not eat, drink, or smoke while using the product
Packaging Materials: Compatible with stainless steel, HDPE, and glass containers
Occupational Exposure Limit: AIHA WEEL 10 mg/m³ TWA for aerosolized forms or as vapor
Engineering Controls: Use local exhaust ventilation if vapor or mist generated
Protective Equipment: Safety goggles, gloves (nitrile, PVC, or similar), lab coat
Respiratory Protection: Not usually required under normal conditions; use mask if mist present
Personal Hygiene: Wash after handling, change contaminated clothing promptly
Appearance: Clear, colorless, viscous liquid
Odor: Faint, sweet odor
Odor Threshold: Not established
pH: 6.0–8.0 (50% solution in water)
Melting Point: -59°C
Boiling Point: 188–189°C
Flash Point: 104°C (closed cup)
Evaporation Rate: Very low
Flammability: Not readily flammable
Vapor Pressure: 0.13 hPa at 20°C
Vapor Density: 2.6 (air=1)
Relative Density: 1.035–1.039 g/cm³ at 20°C
Solubility: Miscible with water
Partition Coefficient (log Kow): -0.92
Viscosity: 55–60 mPa·s at 20°C
Chemical Stability: Remains stable under recommended storage conditions
Hazardous Reactions: No dangerous reactions under normal conditions
Materials to Avoid: Strong acids, strong oxidizing agents, alkali metals, chlorinated compounds
Conditions to Avoid: Heat, flames, sources of ignition, long-term exposure to air
Decomposition Products: Carbon monoxide, carbon dioxide, small amounts of organic acids at elevated temperatures
Routes of Exposure: Skin contact, eye contact, ingestion, inhalation of mist
Acute Toxicity: Oral LD50 (rat) 20,000 mg/kg; practically non-toxic
Skin Corrosion/Irritation: Not considered an irritant under standard test conditions
Eye Damage/Irritation: Mild, transient irritation possible
Respiratory Sensitization: Not a respiratory sensitizer
Skin Sensitization: No evidence from studies
Genotoxicity: Not expected to be genotoxic
Reproductive Toxicity: No evidence of reproductive effects
Carcinogenicity: Not listed by IARC, NTP, OSHA, or EU
Chronic Effects: No observed chronic health effects related to normal exposure
Ecotoxicity: Low toxicity to aquatic organisms; EC50 (Daphnia magna, 48h) > 10,000 mg/L
Persistence and Degradability: Rapidly biodegradable in water and soil environments
Bioaccumulative Potential: Does not bioaccumulate (low log Kow)
Mobility in Soil: High mobility due to water solubility
Other Effects: Does not contribute to ozone depletion or global warming under typical use
Waste Treatment Methods: Dispose of in accordance with local, regional, national, and international regulations
Product Disposal: Can be incinerated in approved facilities or discharged to wastewater treatment plants if permitted
Contaminated Packaging: Rinse containers thoroughly, recycle or dispose following local guidance
Special Precautions: Avoid uncontrolled disposal that might contaminate soil, water, or drains
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not marine pollutant
Special Precautions for User: Protect from physical damage and extreme temperatures during transportation
International Inventories: Listed on TSCA, EINECS, Japan ENCS, Australia AICS, Canada DSL/NDSL, China IECSC, Korea ECL, Philippines PICCS
Label Requirements: Complies with global GHS rules, product does not require special hazard labeling
Food and Pharma Regulations: Recognized as Generally Recognized as Safe (GRAS) by US FDA for direct food use, accepted for pharmaceutical use under pharmacopeia standards
Worker Protection: Covered by OSHA (US) general workplace safety standards
Other Standards: REACH compliant, not listed under any chemical restriction lists worldwide
