Chemical Name: Neopentyl Glycol
Synonyms: 2,2-Dimethyl-1,3-propanediol
CAS Number: 126-30-7
Recommended Use: Ingredient in resins, paints, plasticizers, lubricants, adhesives
Manufacturer: Common among global chemical suppliers, including Eastman and BASF
Emergency Contact: Refer to supplier emergency numbers listed on packaging
Classification: Eye irritation (Category 2A), skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, may cause skin irritation
Pictograms: Exclamation mark
Precautionary Statements: Wear protective equipment, avoid contact with eyes and skin, wash hands thoroughly after handling
Potential Health Effects: Can cause redness, watering, and discomfort in eyes, redness and mild itchiness on skin
Component: Neopentyl Glycol
Percentage: >99% by weight
Impurities: Water (<0.1%), possible traces of formic, acetic, propionic acids
Molecular Formula: C5H12O2
Eye Contact: Rinse with running water for 15 minutes, lift eyelids to ensure thorough flushing, seek medical attention if irritation persists
Skin Contact: Wash skin using soap and water, remove contaminated clothing, seek medical attention for persistent symptoms
Inhalation: Move to fresh air, seek medical advice if cough, shortness of breath, or dizziness occur
Ingestion: Rinse mouth, drink water if victim is conscious, do not induce vomiting, consult poison control or a doctor
Most Important Acute Symptoms: Eye irritation, mild skin irritation
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Strong water jet (spreads product)
Special Hazards: During combustion, may release carbon monoxide and carbon dioxide
Advice for Firefighters: Wear self-contained breathing apparatus, use full protective gear
Special Procedures: Prevent runoff from entering drains or waterways, remove containers from fire area if safe
Personal Precautions: Use gloves, goggles, and respirator where dust occurs
Environmental Precautions: Prevent spillage from entering sewers, surface, or groundwater
Methods for Containment: Sweep up without creating dust, transfer to suitable container, ventilate area
Cleanup Procedures: Wash spill area with water after material pickup, dispose in accordance with local regulations
Emergency Procedures: Isolate area, restrict access, notify authorities if large spill reaches waterways
Handling: Avoid dust generation, prevent eye and skin contact, do not eat or drink in work area, follow good hygiene practices
Storage: Keep in tightly sealed container, store in cool, dry, well-ventilated location away from oxidizers and strong acids
Storage Temperature: Store below 30°C
Incompatible Materials: Strong acids, strong oxidizing agents, isocyanates
Special Requirements: Store away from food and beverages, protect from moisture to avoid clumping or degradation
Occupational Exposure Limits: Not established for Neopentyl Glycol by OSHA, ACGIH, or NIOSH
Engineering Controls: Ensure local exhaust or general room ventilation, enclose process if dust or vapor forms
Personal Protective Equipment: Safety glasses with side shields, nitrile or neoprene gloves, long-sleeve protective clothing
Respiratory Protection: Use dust masks or P100 respirator in poorly ventilated settings
Hygiene Measures: Wash hands thoroughly after use, avoid contact with skin and eyes, do not smoke or eat at workstation
Appearance: White crystalline powder
Odor: Very faint, sweet
Odor Threshold: Not established
pH: Slightly acidic to neutral
Melting Point: 124–128°C (255–262°F)
Boiling Point: 208°C (406°F) at 760 mmHg
Flash Point: >143°C (290°F) (closed cup)
Evaporation Rate: Not measured
Flammability: Not easily ignited; combustible at high temperature
Vapor Pressure: <0.01 hPa at 20°C
Solubility: Soluble in water, alcohols, acetone
Partition Coefficient (log Kow): -0.7
Viscosity: Not applicable (solid)
Density: About 1.06 g/cm³ at 20°C
Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Does not react violently under general conditions
Possible Hazardous Reactions: Exothermic reaction possible with strong oxidizers or acids
Conditions to Avoid: Excessive heat, open flame, contact with strong acids or oxidizing agents
Incompatible Materials: Chlorinated compounds, strong oxidizers, strong acids
Hazardous Decomposition Products: Carbon oxides during burning, may release harmful vapors at decomposing temperatures
Acute Toxicity: Oral LD50 (rat): >4000 mg/kg; low toxicity by dermal or oral route
Skin Corrosion/Irritation: Mildly irritating, not a sensitizer in standard patch testing
Serious Eye Damage/Irritation: Can cause transient moderate irritation
Inhalation: Dust may mildly irritate respiratory tract
Chronic Effects: No evidence of long-term carcinogenic, mutagenic, or reproductive toxicity effects in animal studies
Sensitization: Did not cause sensitization in skin or respiratory tract animal models
Other Information: Not classified as carcinogen by IARC, NTP, OSHA, or EU regulation
Ecotoxicity: Not acutely toxic to aquatic life in standard tests (EC50 > 100 mg/L for fish, daphnia, and algae)
Persistence and Degradability: Readily biodegradable under aerobic conditions, expected half-life in soil and water is low
Bioaccumulative Potential: Low, log Kow value is negative, indicating low potential for bioaccumulation
Mobility in Soil: High water solubility, can migrate with water through soil
Other Adverse Effects: Not identified as toxic to the ozone layer, not expected to contribute to bioaccumulative pollution
Waste Disposal: Dispose through licensed chemical waste contractor, follow all federal, state, and local environmental control regulations
Contaminated Packaging: Rinse with water, send for recycling or disposal as hazardous waste, do not reuse without decontamination
Sewage Disposal: Do not pour into drains, waterways, or soil
Recommended Disposal Methods: Incineration in approved facility, landfilling where permitted under authority guidance
UN Number: Not assigned; not regulated as hazardous cargo
Proper Shipping Name: Neopentyl Glycol
Transport Hazard Class: Non-hazardous
Packing Group: Not regulated
Marine Pollutant: No
Special Precautions: Use sealed, labeled packaging, store away from strong oxidizers, avoid dropping or spilling to prevent dust
US TSCA Status: Listed
REACH Status: Registered in EU under Article 10
OSHA HazCom: Hazardous chemical under the OSHA Hazard Communication Standard (29 CFR 1910.1200)
SARA 313: Not subject to reporting
California Prop 65: Not listed
Canada DSL/NDSL: Listed
Japan ENCS: Listed
Australia AICS: Listed
Other Regulations: Complies with all local, national, and international guidelines for safe handling and use
