Material Safety Data Sheet: N-Propanol

Identification

Product Name: N-Propanol
Chemical Name: 1-Propanol
Other Names: Propan-1-ol, Propyl Alcohol, n-Propyl alcohol
CAS Number: 71-23-8
Recommended Use: Solvent for resins and pharmaceuticals, chemical intermediate, cleaning agent
Manufacturer: [Manufacturer Name]
Emergency Phone: [Contact Number]
Address: [Manufacturer Address]

Hazard Identification

GHS Classification: Flammable liquids (Category 2), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3)
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor, May cause drowsiness or dizziness, Causes serious eye irritation
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames, and hot surfaces. Avoid breathing vapors or mist. Wear protective gloves and eye protection. In case of inadequate ventilation, wear respiratory protection.

Composition / Information on Ingredients

Chemical Name: 1-Propanol
Concentration: 99% or greater
CAS Number: 71-23-8
Impurities/Additives: No significant impurities expected under normal storage and handling conditions.

First Aid Measures

Inhalation: Move the exposed person to fresh air. Seek medical advice if symptoms persist, such as coughing, dizziness, or shortness of breath.
Skin Contact: Remove contaminated clothing. Wash affected area thoroughly with soap and water. Seek medical attention if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing, then seek immediate medical attention.
Ingestion: Rinse mouth. If large quantities have been swallowed, do not induce vomiting. Get medical attention promptly.

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide, water spray
Unsuitable Extinguishing Media: Direct water stream may spread the fire
Specific Hazards: Forms explosive mixtures with air. Vapors may travel to source of ignition.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing.
Special Exposure Hazards: Can produce toxic gases such as carbon monoxide and carbon dioxide under fire conditions.
Advice for Firefighters: Remove containers from fire area if it can be done safely. Cool adjacent containers with water spray to prevent pressure build-up.

Accidental Release Measures

Personal Precautions: Wear protective equipment including gloves, goggles, and suitable protective clothing. Shut off ignition sources. Ventilate the area.
Environmental Precautions: Prevent spill from entering sewers or watercourses. Notify authorities if a significant amount enters environment.
Spill Containment: Absorb small spills with inert material such as sand or earth. Transfer to a suitable container for proper disposal.
Decontamination: Clean area with water and detergent, ventilate well. Collect and dispose of residues per local regulations.

Handling and Storage

Handling: Use only in well-ventilated areas. Ground and bond containers when transferring liquid. Avoid contact with skin, eyes, and clothing. Do not breathe vapors or sprays.
Storage: Store in tightly closed, properly labeled containers. Keep away from heat, sparks, flames, or other sources of ignition. Store in a cool, dry, and well-ventilated location. Keep away from incompatible substances including strong oxidizing agents, acids, and bases. Ensure access to emergency eyewash and safety showers at storage areas.

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL: 200 ppm (TWA), ACGIH TLV: 100 ppm (TWA), 150 ppm (STEL)
Engineering Controls: Use local exhaust ventilation to control exposure. Keep concentrations below legal exposure limits.
Personal Protective Equipment: Wear chemical-resistant gloves, splash-proof goggles, and flame-retardant clothing. Provide suitable respiratory protection when ventilation is not adequate.
Hygiene Measures: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse.

Physical and Chemical Properties

Appearance: Colorless liquid
Odor: Mild, alcohol-like
Odor Threshold: 10-50 ppm
pH: Not available
Melting Point/Freezing Point: -126°C (-194.8°F)
Boiling Point: 97°C (206.6°F)
Flash Point: 15°C (59°F)
Evaporation Rate: 1.3 (butyl acetate = 1)
Flammability: Highly flammable
Vapor Pressure: 20 mm Hg at 20°C
Vapor Density: 2.07 (air = 1)
Relative Density: 0.803 g/cm³ at 20°C
Solubility: Miscible in water
Partition Coefficient (n-octanol/water): 0.25 (log Pow)
Auto-ignition Temperature: 399°C (750°F)
Decomposition Temperature: Not established
Viscosity: 2.7 cP at 20°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong oxidizing agents, strong acids, and bases
Hazardous Reactions: Vapors may form explosive mixtures with air
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and other toxic fumes
Polymerization: Will not occur under normal conditions

Toxicological Information

Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: LD50 (oral, rat): 1870 mg/kg, LD50 (dermal, rabbit): 5040 mg/kg, LC50 (inhalation, rat, 4h): 20,000 ppm
Chronic Effects: May cause central nervous system depression, prolonged or repeated exposure may cause kidney and liver effects
Symptoms of Exposure: Headache, dizziness, drowsiness, nausea, irritation to eyes and respiratory tract
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No data suggesting mutagenic hazard for humans under normal use
Reproductive Toxicity: Animal studies show possible reproductive effects at high doses, relevance to human exposure not confirmed

Ecological Information

Ecotoxicity: Toxic to aquatic organisms at high concentrations, LC50 (fish, 96 hr): ~3800 mg/L
Persistence and Degradability: Readily biodegradable under aerobic conditions
Bioaccumulative Potential: Low potential for bioaccumulation (log Kow: 0.25)
Mobility in Soil: High mobility in soil; not expected to bind strongly to soils
Other Adverse Effects: Not expected to cause long-term adverse effects in the environment when used and disposed of correctly

Disposal Considerations

Waste Disposal: Dispose in accordance with local, regional, national, and international regulations. Incineration or disposal by an approved chemical waste facility recommended.
Contaminated Packaging: Rinse containers thoroughly before recycling or disposal. Dispose of residues according to hazardous waste regulations.
Special Precautions: Do not flush into surface water or sanitary sewer systems. Consult local authorities for specific guidance.

Transport Information

UN Number: UN1274
Proper Shipping Name: Propanol, n- (1-Propanol)
Hazard Class: 3 (Flammable Liquid)
Packing Group: II
Labels: Flammable liquid
Transport in Bulk: According to Annex II of MARPOL and IBC Code
Special Precautions: Keep away from heat, sparks, and open flames during transport. Ensure strict compliance with all applicable regulations related to shipment of hazardous materials.

Regulatory Information

OSHA: Hazardous under OSHA Hazard Communication Standard, 29 CFR 1910.1200
TSCA: Listed in TSCA Inventory
SARA Title III: Section 302 (no), Section 311/312 (fire hazard, acute health hazard), Section 313 (no)
REACH: Registered substance in Europe
DSL/NDSL (Canada): Listed
Other Regulations: Subject to additional regulations in some states or countries. Consult local regulatory agencies for complete details.