Product Name: Fluorobenzene
Chemical Formula: C6H5F
CAS Number: 462-06-6
Synonyms: Monofluorobenzene, Phenyl fluoride
Recommended Use: Laboratory chemicals, industrial solvent, synthesis intermediate
Manufacturer/Supplier: Refer to supplier documentation for details
Emergency Contact: Refer to local national poison centers or emergency services for immediate advice on exposure and incidents
Company Contact Email: Refer to supplier documentation
GHS Classification: Flammable liquid (Category 3), Acute toxicity, inhalation (Category 4), Skin and eye irritant (Category 2A), Specific target organ toxicity - single exposure (Category 3)
Signal Word: Warning
Hazard Statements: H226: Flammable liquid and vapor; H332: Harmful if inhaled; H319: Causes serious eye irritation; H335: May cause respiratory irritation
Precautionary Statements: P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking; P261: Avoid breathing dust/fume/gas/mist/vapors/spray; P280: Wear protective gloves, protective clothing, and eye protection; P305+P351+P338: If in eyes, rinse cautiously with water for several minutes, remove contact lenses if present
Chemical Name: Fluorobenzene
Concentration: Greater than 99% (by weight)
Impurities: Commercially available samples may contain trace amounts of benzene or difluorobenzene
Molecular Weight: 96.10 g/mol
Other Ingredients: None of concern under typical handling
Inhalation: Move person to fresh air, offer oxygen if breathing is difficult, seek medical attention for persistent symptoms, note any confusion or headache for care provider
Skin Contact: Remove contaminated clothing immediately, wash area with plenty of water and soap for at least 15 minutes, monitor for skin irritation, consult a physician for persistent redness
Eye Contact: Rinse eyes with plenty of water for several minutes, lift eyelids regularly, avoid rubbing eyes, seek prompt medical assistance if discomfort continues
Ingestion: Do not induce vomiting, rinse mouth if conscious, never give anything by mouth to an unconscious person, seek medical advice without delay
Most Important Symptoms: Irritation to eyes, respiratory irritation, drowsiness, headache from inhalation
Suitable Extinguishing Media: Use carbon dioxide, dry chemical, or alcohol-resistant foam
Unsuitable Media: Direct water streams could spread burning liquid
Specific Hazards: Vapors can form explosive mixtures with air, combustion may release toxic fumes of hydrogen fluoride, carbon monoxide, and carbon dioxide
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective gear
Firefighting Procedure: Stay upwind, keep containers cool, avoid inhaling decomposition gases, evacuate area of unnecessary personnel
Personal Protection: Remove all ignition sources, ventilate area, wear chemical-resistant gloves, goggles, and suitable protective clothing
Spill Cleanup: Contain spill with inert absorbent (sand or earth), collect into appropriate labeled containers for disposal
Environmental Precautions: Prevent runoff into drains, sewers, or waterways, avoid soil contamination
Decontamination: Wash spill area with water and detergent following cleanup, ensure proper ventilation before reuse of the space
Safe Handling: Work in well-ventilated spaces, ground and bond containers before transfer, avoid all ignition sources, do not breathe vapors, avoid contact with skin and eyes
Personal Hygiene: Wash hands thoroughly after handling, do not eat, drink, or smoke during use
Storage Requirements: Store in tightly closed containers in a cool, dry, well-ventilated area, keep away from oxidizing agents and strong acids, segregate from incompatible materials
Storage Temperature: Store at room temperature, out of direct sunlight, avoid excessive heat
Occupational Exposure Limits: Consult national or regional agencies for current recommended exposure limits
Engineering Controls: Use local exhaust or general ventilation to maintain vapor concentrations below recommended limits
Personal Protective Equipment: Wear splash-proof chemical goggles, nitrile gloves, lab coat or apron, and, for high vapor concentrations, an organic vapor respirator
Environmental Controls: Install spill containment where large quantities are stored, ensure eyewash stations and safety showers remain accessible
Appearance: Clear, colorless liquid
Odor: Pleasant, ether-like, slightly sweet
Odor Threshold: Low, detectable at low concentrations
pH: Not applicable
Melting Point: –44 °C
Boiling Point: 85–86 °C
Flash Point: 18 °C (closed cup)
Evaporation Rate: Fast (compared to water)
Flammability: Flammable liquid
Vapor Pressure: 28 mm Hg at 25 °C
Vapor Density: 3.3 (air = 1)
Relative Density: 1.024 at 20 °C
Solubility: Slightly soluble in water, easily mixes with most organic solvents
Partition Coefficient (n-octanol/water): 2.8 log Pow
Autoignition Temperature: 575 °C
Decomposition Temperature: No data available
Viscosity: Low; flows readily
Chemical Stability: Stable under normal storage and handling
Possibility of Hazardous Reactions: May form peroxides, reacts with strong oxidizers and acids
Conditions to Avoid: Avoid heat, sparks, open flame, and incompatible materials
Incompatible Materials: Alkali metals, strong acids, oxidizing agents, nitrates
Hazardous Decomposition Products: Toxins such as hydrogen fluoride, carbon monoxide, and carbon dioxide on combustion
Acute Toxicity: Inhalation LC50 (rat): around 25,000 mg/m³ (4-hour exposure); oral LD50 (rat): approximately 2,000 mg/kg; dermal LD50 exceeds 2,000 mg/kg
Chronic Effects: Prolonged or repeated exposure may cause skin dryness and cracking, respiratory irritation, and dizziness
Routes of Exposure: Inhalation, skin and eye contact, incidental ingestion
Symptoms: Drowsiness, headache, eye redness, coughing, sore throat
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Mutagenicity: No significant mutagenic risk found in standard tests
Other Risks: High vapor concentrations may cause narcosis
Ecotoxicity: Moderately toxic to aquatic life; EC50 (Daphnia): 11 mg/L (48 hours); LC50 (Fish): 38 mg/L (96 hours)
Persistence and Degradability: Not rapidly biodegradable; some photodegradation in air
Bioaccumulation Potential: Moderate (log Pow 2.8), may accumulate in aquatic organisms
Mobility in Soil: Moderate; volatilizes from soil surface under typical conditions
Environmental Concerns: Spillages and discharges may impact water bodies, aquatic life, and soil organisms
Waste Disposal: Dispose of as hazardous chemical waste in accordance with local, state, and national regulations
Recommended Methods: Incineration in chemical incinerators with afterburner and scrubber for fluorinated waste, avoid flushing to waterways
Container Disposal: Triple rinse emptied containers before disposal, destroy by controlled chemical incineration, never reuse empty containers
Precautions: Follow all local environmental protection and health and safety guidelines during handling and disposal procedures
UN Number: UN2387
UN Proper Shipping Name: Fluorobenzene
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Environmental Hazards: Harmful to aquatic life, proper labels required
Special Precautions: Keep container upright and tightly sealed, store and transport away from sources of ignition, follow regulations for flammable liquids transport
OSHA: Covered under Hazard Communication Standard; classified as hazardous
TSCA: Listed
SARA Title III: Not subject to reporting under Section 313
European Regulations: Listed in EINECS, REACH registration required for large quantities
WHMIS Classification (Canada): B2 (Flammable liquid), D2B (Toxic by inhalation or skin contact)
Other Regulations: Always check specific local, state, and federal listings for the substance
Labeling Requirements: Appropriate hazard and precautionary statements must appear on labels in compliance with GHS and local codes
