Product Name: 1,3-Butanediol Glycol
Chemical Name: 1,3-Butanediol
Synonyms: 1,3-Butylene Glycol, 1,3-Dihydroxybutane, Butane-1,3-diol
Molecular Formula: C4H10O2
Molecular Weight: 90.12 g/mol
Recommended Use: Chemical intermediate, solvent, humectant, components in cosmetics and pharmaceuticals
Supplier Details: Name, address, emergency contact, phone, email of the chemical provider
Emergency Numbers: Local emergency services, CHEMTREC, poison control center
GHS Classification: Not classified as hazardous according to GHS criteria for this substance
Main Hazards: May cause slight eye irritation; skin contact can lead to mild irritation in sensitive individuals; can be harmful if ingested in large amounts; vapor may cause mild respiratory discomfort in poorly ventilated spaces
Pictogram: No mandatory symbol for this substance at standard concentrations
Signal Word: Warning
Hazard Statements: May cause temporary eye discomfort; ingestion in large volumes could generate central nervous system effects
Precautionary Statements: Avoid direct contact with eyes and extensive skin exposure; do not ingest; maintain adequate ventilation during handling
Chemical Name: 1,3-Butanediol
CAS Number: 107-88-0
EC Number: 203-529-7
Concentration: > 99% by weight
Impurities: Water (< 1%); trace-level organic residues typical for synthesis routes
Other Components: No deliberately added stabilizers or non-declared additives
Eye Contact: Immediately rinse thoroughly with clean water for 10 to 15 minutes, holding eyelids open, remove contact lenses if present, seek medical attention only if symptoms persist
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, seek advice if irritation develops or persists
Inhalation: Move affected person to fresh air, keep them at rest, seek medical help if symptoms such as cough, dizziness, or respiratory irritation persist
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, consult a physician if anyone feels unwell or if large amounts are swallowed
Most Important Symptoms: Mild irritation, headache, possible drowsiness with significant ingestion
Advice for Medical Personnel: Treat symptomatically based on patient response
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: Direct water jet due to spread of burning material
Specific Hazards: Combustion produces carbon monoxide, carbon dioxide, small amounts of aldehydes
Protective Equipment: Self-contained breathing apparatus and full protective gear for fire situations
Special Procedures: Move containers from fire area if it can be done safely, use water to cool nearby containers, keep upwind to avoid vapors
Explosion Risk: Product is not highly flammable but may emit flammable vapors when heated
Personal Precautions: Wear gloves and safety goggles, avoid breathing vapors, ensure adequate ventilation, remove sources of ignition
Environmental Precautions: Prevent entry into sewers, drains, or waterways, contain spill with inert absorbent (sand, vermiculite)
Cleanup Methods: Absorb with inert material, collect in a suitable container for disposal, clean contaminated surfaces with water and detergent
Special Notes: Dispose in accordance with local regulations; small spills can be diluted with water and mopped up
Handling: Use non-sparking tools, handle with chemical-resistant gloves, avoid eye and prolonged skin contact, ensure proper ventilation at workstations
Storage: Store in tightly sealed containers at room temperature, away from heat and direct sunlight, keep away from strong oxidizers or acids
Incompatibilities: Strong acids, strong oxidizers, avoid storage with reactive metals
Packaging Materials: Use containers made from compatible plastics or stainless steel
Exposure Limits: No established occupational exposure limits (OSHA, ACGIH TLV), maintain low vapor concentrations
Engineering Controls: Local exhaust ventilation, general room ventilation for large-scale use
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile, neoprene), long-sleeved clothing
Respiratory Protection: Respirator with organic vapor cartridge in case of insufficient ventilation, not usually required for normal use
Hygienic Practices: Wash hands thoroughly after handling, no eating or drinking near chemical use
Appearance: Clear, colorless, oily liquid
Odor: Mild sweet odor
pH: Approximately neutral (6–8) in solution
Melting Point: -50°C
Boiling Point: 207°C
Flash Point: 114°C (closed cup)
Evaporation Rate: Low
Flammability: Not classified as highly flammable, combustible at high temperatures
Vapor Pressure: < 0.1 mmHg at 20°C
Solubility: Fully miscible with water
Density: 1.0 – 1.01 g/cm³ at 20°C
Partition Coefficient (n-octanol/water): log Pow: -0.06
Viscosity: Moderate, 25 mPa·s at 20°C
Chemical Stability: Stable under normal use and storage conditions
Conditions to Avoid: Excessive heat, open flames, direct sunlight
Incompatible Materials: Strong acids, oxidizers, reactive metals like sodium
Decomposition Products: Carbon monoxide, carbon dioxide, traces of aldehydes at high temperatures or combustion
Hazardous Reactions: No dangerous reactions known under standard conditions; avoid high energy sources
Acute Toxicity: Oral LD50 (rat): 1650 mg/kg
Inhalation Toxicity: Not expected to cause inhalation toxicity at ordinary temperature
Skin Corrosion/Irritation: Very slight to mild skin irritation possible with prolonged contact
Eye Damage/Irritation: Slight irritant
Respiratory Sensitization: Not classified as a respiratory sensitizer
Skin Sensitization: No known cases of allergic skin reaction
Long-term Effects: Not known to cause cancer or reproductive toxicity, not classified as mutagenic
Symptoms of Overexposure: Drowsiness, mild nausea, eye discomfort, headache if ingested in large doses
Aquatic Toxicity: Low toxicity to fish and aquatic invertebrates (LC50 > 100 mg/L for freshwater fish)
Persistence and Degradability: Readily biodegradable, undergoes rapid breakdown in water and soil
Bioaccumulation Potential: Low, no significant build-up in aquatic or terrestrial organisms (log Pow -0.06)
Mobility in Soil: High, fully soluble in water, leaching into groundwater possible
Other Adverse Effects: Not classified as hazardous to the ozone layer
Waste Treatment Methods: Collect in marked containers for chemical waste, dispose according to local and national regulations
Contaminated Packaging: Rinse empty containers with water before recycling or disposal; follow chemical waste guidelines
Disposal Recommendation: Small amounts can be diluted with water and disposed down the drain in accordance with local requirements; larger quantities should be handled as hazardous waste by a licensed provider
UN Number: Not regulated
Proper Shipping Name: Non-hazardous substance, not classified as dangerous goods for transport
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not environmentally hazardous according to transport regulations
Special Precautions: No special requirements for transportation under normal circumstances; prevent container leaks and spills
US TSCA Inventory: Listed
REACH (EU): Registered for relevant uses in the European Union
SARA Title III Sections 302/304/313: Not listed
California Proposition 65: Not listed as a carcinogen or reproductive toxicant
Canadian DSL/NDSL: Listed on Domestic Substances List (DSL)
Labeling Requirements: No hazardous pictograms or statements required at standard concentration
Occupational Restrictions: No specific restrictions aside from general industrial hygiene measures
References: Data drawn from established regulatory databases, chemical manufacturers, government agencies, and international safety standards
