Chemical Name: 1,2-Octanediol
CAS Number: 1117-86-8
Synonyms: Caprylyl Glycol, 1,2-Dihydroxyoctane
Recommended Use: Ingredient in cosmetics, personal care products, and some industrial applications
Supplier: Contact manufacturer for specific details and emergency phone numbers
Formula: C8H18O2
Molecular Weight: 146.23 g/mol
Product ID: Available from chemical supplier documentation
GHS Classification: Irritant; not classified as hazardous by OSHA (US) under standard conditions
Signal Word: Warning
Hazard Statements: May cause mild skin and eye irritation
Pictograms: Exclamation Mark (for minor irritation)
Precautionary Statements: Avoid contact with eyes and skin. Wash hands after handling.
Potential Health Effects: May trigger eye redness, itching, or mild skin sensitivity in prolonged exposure
NFPA Ratings: Health: 1, Flammability: 1, Reactivity: 0
Chemical Ingredient: 1,2-Octanediol
Purity: Typically 98% or higher in commercial grades
Impurities: Trace water, possible trace isomers/templates below reporting thresholds
Stabilizers/Additives: None required for material stability
Inhalation: Move person to fresh air if dust or vapor is inhaled. Seek medical attention if symptoms persist.
Skin Contact: Wash exposed area with soap and water. Remove contaminated clothing. If skin irritation develops, consult a physician.
Eye Contact: Rinse immediately with clean water for at least 15 minutes and avoid rubbing the eyes. Get medical help if irritation continues.
Ingestion: Rinse mouth. Call a doctor if feeling unwell or if large quantities are ingested.
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide extinguishers.
Unsuitable Media: Direct water jets may cause spattering.
Specific Hazards: Burning releases carbon oxides; may produce irritating fumes.
Protective Equipment: Wear full protective gear and NIOSH-approved self-contained breathing apparatus.
Special Procedures: Use caution when approaching fire, avoid inhaling decomposition products.
Personal Precautions: Ventilate the spill area, avoid direct skin and eye contact, wear gloves and goggles.
Environmental Precautions: Prevent large spills from reaching waterways or drains.
Containment Methods: Absorb with inert material like sand or vermiculite.
Cleanup Procedures: Collect residue in sealable containers for proper disposal according to regulations.
Reporting Requirements: Notify authorities if significant quantities enter the environment.
Handling: Use appropriate personal protective equipment (PPE), work in well-ventilated spaces.
Storage Conditions: Store tightly closed in a cool, dry, and well-ventilated area, away from reactors or strong oxidizers.
Incompatible Materials: Keep away from strong acids, strong bases, and oxidizing agents.
Safe Transfer: Use closed systems or local exhaust when transferring bulk material.
Hygiene Practices: Clean hands and exposed skin before eating, drinking, or smoking after work.
Occupational Exposure Limits: No established OSHA or ACGIH limits; control exposures using good industrial hygiene practices.
Engineering Controls: Use local exhaust, fume hoods, or adequate general ventilation.
Personal Protective Equipment: Use safety goggles, protective gloves (nitrile or neoprene), and lab coats.
Respiratory Protection: Use NIOSH-approved respirator if dusts or vapors exceed safe levels.
Environmental Controls: Avoid release into the environment during cleaning or disposal.
Appearance: Clear to pale yellow liquid
Odor: Faint, sweet
Odor Threshold: Not readily established
pH: 6 – 8 (10% solution in water)
Melting Point: 25 - 28 °C
Boiling Point: 251 – 253 °C
Flash Point: >110 °C
Evaporation Rate: Not rapidly evaporating at room temperature
Flammability: Not easily flammable
Vapor Pressure: <0.01 mmHg (20°C)
Vapor Density: Not available
Relative Density: 0.92 - 0.94 g/cm³ (20°C)
Solubility: Miscible with water, ethanol, glycols
Partition Coefficient (n-octanol/water): log Kow = 1.10 - 2.61
Auto-ignition Temperature: >200°C
Decomposition Temperature: >200°C
Viscosity: 40-60 mPa·s (25°C)
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Not highly reactive, but may react with strong oxidizers.
Conditions to Avoid: Strong heat, direct sunlight, and incompatible materials.
Incompatible Materials: Strong oxidizers, acids, alkalis.
Hazardous Decomposition Products: Emits carbon oxides and possibly aldehydes when heated to decomposition.
Polymerization: Does not polymerize.
Likely Routes of Exposure: Skin contact, eye contact, ingestion.
Acute Effects: May cause irritation to skin and eyes; not highly toxic.
LD50 (Oral, Rat): 3,200 mg/kg (literature value)
LD50 (Dermal): Not expected to be acutely toxic by dermal route.
Chronic Effects: Little evidence for chronic toxicity; prolonged contact may cause dryness or irritation.
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA.
Mutagenicity/Teratogenicity: No signs of mutagenic or teratogenic effects in available studies.
Target Organs: Eyes, skin (in rare, sensitive cases).
Ecotoxicity: Not expected to be highly toxic to aquatic organisms. LC50 (fish): >100 mg/L.
Persistence and Degradability: Readily biodegradable in the environment.
Bioaccumulative Potential: Bioaccumulation unlikely due to water solubility and degradation.
Mobility in Soil: Expected to have high mobility due to solubility in water.
Other Adverse Effects: No known significant effects or hazards.
Safe Disposal Methods: Dispose in accordance with local, regional, and national regulations.
Incineration: Can be incinerated in an industrial facility if permitted.
Landfill: Small amounts may be permitted in landfill after solidification and approval.
Container Disposal: Rinse containers well, then send for recycling or disposal under chemical waste guidelines.
Precautions: Do not dispose in household garbage, sanitary sewer, or waterways.
UN Number: Not regulated for transport by road, rail, sea, or air.
UN Proper Shipping Name: Not regulated.
Transport Hazard Class: Not classified.
Packing Group: Not assigned.
Special Precautions: Keep containers tightly sealed and secure during transport to prevent leaks or spills.
Environmental Hazards: No restrictions regarding marine pollutant status.
Transport Labels: None required for normal quantities.
TSCA: Listed on the US Toxic Substances Control Act inventory.
EINECS/ELINCS (Europe): Listed.
REACH Status: Pre-registered or registered within the EU.
Canadian DSL/NDSL: Listed.
Australian AICS: Listed.
Other Country Inventories: May be listed in countries such as Japan, China, Korea, New Zealand.
SARA 313: Not subject to reporting requirements.
California Proposition 65: Not listed.
WHMIS Classification (Canada): Not controlled.
Other Regulatory Notes: Always review local regulations for workplace controls and public safety.
